Clinical symptoms caused by uterine fibroid include pelvic pain or compression, abnormal uterine bleeding, gastrointestinal and voiding problems. The prevalence of uterine fibroids is predicted to be approximately 70% depending on the population. It is not usually fatal but can produce serious clinical symptoms. It affects the normal life of thousands of women of childbearing age, especially non-Caucasian women, which can be caused by genetic and environmental factors.
Uterine fibroids are common benign muscle tumors of the uterus. *Address all correspondence to: Background Cancer Center, Wan-Fung Medical Center, Taipei Medical University, Taiwan.
TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taiwan. Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, USA. School of Pharmacy, Taipei Medical University, Taiwan. Graduate Institute of Nanomedicine and Medical Engineering, College of Medical Engineering, Taipei Medical University, Taiwan. Graduate Institute of Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taiwan. We also address the possibility of using herbal medicines for uterine fibroid treatment. In the current review article, we discuss signal transduction pathways activated herbal medicines. Exploring herbal medicines as remedies lighten the hope of treatment. All of them have a common capability to inhibit expression of pro-inflammatory cytokines, proliferative genes, and pro-angiogenetic genes. Several herbal medicines have been used as anti-inflammation and antitumor agents. Sex steroid hormones, dysregulation of cell signaling pathways, miRNA expression, and cytogenetic abnormalities may all implicate in fibroid etiology. The lack of understanding of the etiology of fibroid contributes to the scarcity of medical therapies available. Despite the prevalence of fibroid, currently, there are no effective treatment options for fibroid. Uterine fibroids are the cause of major quality-of-life issues for approximately 25% of all women who suffer from clinically significant symptoms of uterine fibroid. 
Uterine fibroids, also known as uterine leiomyoma is the most common benign tumor of the uterus found in women of reproductive age.
0 kommentar(er)
